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Sleeping medication triples the risks of cancer and death

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Sleeping medication triples the risks of cancer and death

Sleeping Medication and Your Health

Hypnotics, commonly called sleeping pills, are a class of drugs having the property of inducing sleep in individuals who experience difficulty falling asleep or early awakenings. Although they may work for a certain time they are not safe. But why people use sleeping medication so often in the US?

Those who never suffer from chronic insomnia may not be able to understand. But all insomniacs know that in despair to have good night sleep they would resort to ant thing, including “strong sleeping pills”. In fact, almost half of the US population tries some form of soporific drugs (sleeping medication) at some point in their life.Injuries Caused By Common Sleep Medications | Levin & Perconti

Sleep disorders are serious concern for most, and a very profitable business for the drug companies.  These pills cannot help on the long-term; they provide an immediate solution with potential long term side effects. Even people who don’t have serious adverse reactions tend to experience these minors conditions:

  • Constipation
  • Dizziness
  • Impaired concentration and memory
  • Stomach aches
  • Weakness
  • Anger (in about 5% of cases).

Most sleeping pills work by depressing or slowing down the body’s functions in order to induce and maintain sleep. They are classified in the group of sedative-hypnotics. Among the sedative-hypnotics are benzodiazepines and barbiturates. Benzodiazepines, such as Xanax and Valium, can be addictive and potentially life-threatening. Barbiturates depress the central nervous system and are used as an anesthetic and sedatives. As with all drugs, sleeping medication come with side effects.


Sleeping Medication Side Effects

Sleeping pills cause many side effects, among them alertness impairment and short-term memory problems. For instance Zolpidem has been, in rare cases, associated with sleepwalking, obesity, and amnesic syndrome: a mental disorder characterized by acquired impairment in the ability to learn and recall new information, sometimes accompanied by inability to recall previously learned information.

Death and Certain Cancers – Sleep medication can be associated with a slight reduction of Rapid eye movement sleep (REM sleep, REMS) and an increase of snoring as well as risk of obstructive sleep apnea. Taking certain hypnotics is associated with an increased risk of occurrence of certain cancers, including skin cancer. It is also associated with an increased risk of death, according to strong evidence based on the link between depression and increased mortality.shutterstock_102818147-688x353 - Laboratorios Metro Other evidence including scientific findings respectively published in 1979, 1998, 2009, 2010, confirmed in February 2012 by a new US study involving more than 10,000 patients who had been prescribed zolpidem, temazepam, Eszopiclone, zaleplon, other benzodiazepines, barbiturates and sedating antihistamines. These studies concluded that the risk of death among users of those sleeping pills is four times higher than in the general population.

With less than 18 pills per year, the risk of death for these patients was already tripled, and then the risk increases even higher with taking high doses. That is, people who take sleeping pills daily multiply the risk of premature death considerably more than the insomnia itself. The authors of the studies state that the risk of death and cancer associated with hypnotic drugs could not be due to pre-existing disease. They do not, however, find any relation between the use of melatonin and the risk of any medical condition. A whole chapter is dedicated to Melatonin; please read it for more information.

Falls and Bone Fractures – In the elderly, taking sleeping pills is associated with an increased risk of falls and fractures of the femoral neck, which is located near the top of the femur bone connecting the femoral head with the femoral shaft. It is also associated with increased risk of cognitive disorders and cardiac disorders. Fatigue in Older Adults | National Institute on AgingIn subjects over 60 years sleeping medication the risks of fatigue, cognitive problems, headaches, nightmares, nausea, and others…

Because residues of these drugs are found in significant and increasing amounts in sewage plant, even in some natural environment, certain scientist question possible ecoepidemiologic and ecological effects of their increasing use. Worst, in some consumers these medications increase their sleep to just one hour or less. For people they really work, for a short time, these drugs tend to cause addiction, paradoxical effects: depression, anger attacks, and others.

Addiction – People taking certain sleeping pills may be fast (weeks or months) dependent on them especially since their sleep quality gets worse with the use of these hypnotics. Various studies confirm these drugs can cause some dependency: It is now well known that the tranquilizers and sleeping pills in the benzodiazepine can cause drug dependence, even when so-called therapeutic doses are taken, even after a brief treatment. The discovery of this risk is relatively recent; most consumers have no clue they spend their money to kill themselves.

Paradoxical Effect – Side effects such as depression, with or without suicidal tendencies, phobic states, aggressive and violent behavior may occur in 5% of cases according to Professor Malcolm Lader of the Institute of Psychiatry, Psychology & Neuroscience, King’s College London. This conclusion has been reached based on 7 million people (figure published in 2001) in France who consume sleeping pills, of which 350,000 experience paradoxical effects.

Although In the US, some manufacturers consider it a duty to report these side effects and report the risk of depression, anxiety, and others, several drug manufacturers and distributors are silent about these damaging side effects, although they are well-documented in the medical literature.

Because these reactions are often interpreted as symptoms of a worsening condition of the person concerned, many patients become drug-dependent for the same reason they have serious side effects. Tragically, sleeping medication business is booming. One critic, Daniel Yi, states on LA Times, “the use of prescription sleeping pills is up nearly 50% since 2001, and a report released Monday by Consumers Union of United States Inc., publisher of Consumer Reports magazine, attributes at least part of the increase to a surge in direct-to-consumer advertising of such anti-insomnia medications such as Ambien and Lunesta.”


Brunton, Laurence L.; Lazo, John S.; Lazo Parker, Keith L. (2006). “17: Hypnotics and Sedatives”. Goodman & Gilman’s The Pharmacological Basis of Therapeutics (11th ed.). The McGraw-Hill Companies, Inc. ISBN 0-07-146804-8. Retrieved 2014-02-06.

National Prescribing Service (2 February 2010). “NPS News 67: Addressing hypnotic medicines use in primary care”. Retrieved May 10, 2016.

Mendels, J. (September 1991). “Criteria for selection of appropriate benzodiazepine hypnotic therapy”. J Clin Psychiatry. 52. Suppl: 42–6. PMID 1680126.

Gelder, M.; Mayou, R.; Geddes, J. (2005). Psychiatry (3rd ed.). New York: Oxford. p. 238.

Glass, J.; Lanctôt, K. L.; Herrmann, N.; Sproule, B. A.; Busto, U. E. (November 2005). “Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits”. BMJ 331 (7526): 1169. doi:10.1136/bmj.38623.768588.47. PMC 1285093. PMID 16284208.

“What’s wrong with prescribing hypnotics?”. Drug Ther Bull 42 (12): 89–93. December 2004. doi:10.1136/dtb.2004.421289. PMID 15587763. .

Zhdanova, IV (February 2005). “Melatonin as a hypnotic: pro.”. Sleep medicine reviews 9 (1): 51–65. doi:10.1016/j.smrv.2004.04.003. PMID 15649738.

Pacific Record of Medicine and Surgery – Volume 5 – Page 36 1890

Löscher, W.; Rogawski, M. A. (2012). “How theories evolved concerning the mechanism of action of barbiturates”. Epilepsia 53: 12–25. doi:10.1111/epi.12025. PMID 23205959.

Chen, K.; Wang, K.; Kirichian, A. M. (December 2006). “In silico design, synthesis, and biological evaluation of radioiodinated quinazolinone derivatives for alkaline phosphatase-mediated cancer diagnosis and therapy”. Mol. Cancer Ther. 5 (12): 3001–13. doi:10.1158/1535-7163.MCT-06-0465. PMID 17172404.

“Technology Appraisal Guidance 77. Guidance on the use of zaleplon, zolpidem and Eszopiclone for the short-term management of insomnia” (PDF). National Institute for Clinical Excellence. April 2004. Retrieved May 10, 2016.

Ramakrishnan, K.; Scheid, D. C. (August 2007). “Treatment options for insomnia”. American Family Physician 76 (4): 517–26. PMID 17853625.

Ashton, Heather (2005-05-01). “The diagnosis and management of benzodiazepine dependence”. Current Opinion in Psychiatry 18 (3): 249–255. doi:10.1097/01.yco.0000165594.60434.84. ISSN 0951-7367. PMID 16639148

Wakeling, A. (April 1983). “Efficacy and side effects of mianserin, a tetracyclic antidepressant”. Postgrad Med J 59 (690): 229–31. doi:10.1136/pgmj.59.690.229. PMC 2417496. PMID 6346303.

Hartmann, P. M. (January 1999). “Mirtazapine: a newer antidepressant”. Am Fam Physician 59 (1): 159–61. PMID 9917581.

Jindal, R. D. (2009). “Insomnia in patients with depression: some pathophysiological and treatment considerations”. CNS Drugs 23 (4): 309–29. doi:10.2165/00023210-200923040-00004. PMID 19374460.

Leucht, S.; Cipriani, A.; Spineli, L.; Mavridis, D.; Orey, D.; Richter, F.; et al. (September 2013). “Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis”. Lancet 382 (9896): 951–962. doi:10.1016/S0140-6736(13)60733-3. PMID 23810019

Daniel Yi | Times Staff Writer, Wake Up: You May Not Need a Pill to Sleep. Retrieved on May 10 2016

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